Gap junction communication channel: peptides and anti-peptide antibodies as structural probes.

856 benzodiazepine photoaffinity labelling site on the GABA, receptor a 1 subunit [ 121. Further, it should be pointed out that an alternative approach to synthetic peptides as antigens for directed antibody production is the use of bacterially produced subunit fragments, and indeed this strategy has been adopted for the GAHA, receptor [13]. In general these antigens, although probably less expensive to produce, are larger and they do not possess the predetermined exquisite specificity of the synthetic peptide.